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Medicine shifts from treating disease late to extending the years a person stays healthy.

Universe v2 (assumed — this link predates the field)· No stated date on this link
igitur.xyz/b/medicine-shifts-from-treating-disease-late-moqte7
VRTX25.9%
ILMN23.1%
REGN18.8%
XBI10.5%
CRSP5.7%
SGOV16%
Lead positionConviction, descendingBallastWidths are weights · total 100%

Every holding, and why it is that size

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How concentrated this is

Holdings6
Weighted like5.1 equal ones
LargestVRTX at 25.9%
Half the portfolio3 names
Exposed to the premise84%

84% of this book is one theme. It is a bet on Healthspan, not a spread of them.

25.9%Vertex Pharmaceuticals
Genetic medicine that already generates cash, not just readouts.
VRTX · Equity · $521.12 · — · Healthspan
+×
23.1%Illumina
Sequencing is the instrument layer under everything genetic.
ILMN · Equity · $201.27 · — · Healthspan
+×
18.8%Regeneron
An antibody platform that has produced beyond one franchise.
REGN · Equity · $807.65 · — · Healthspan
+×
10.5%Biotech ETF
Spread across small-cap biotech, where single-name risk is brutal.
XBI · ETF · $8.62 · $69B · Healthspan
+×
5.7%CRISPR Therapeutics
Approved editing therapy, tiny commercial base, wide outcomes.
CRSP · Equity · $247.42 · $463B · Healthspan
+×
16%0–3 Month Treasury Bill ETF
Cash that still earns while the thesis is early.
SGOV · Treasury · $100.50 · — · Ballast
The case for
Metabolic drugs turned out to affect far more than weight. Sequencing costs fell far enough to make genetic medicine economic, and the payer is a demographic wave already here.
The case against
Drug pricing is a political target in every developed market. Patents expire on schedule, trials fail late and expensively, and the largest products already carry near-perfect expectations.

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igitur.xyz/b/medicine-shifts-from-treating-disease-late-moqte7
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